Is Augmentin in the Safe Family as Rocephin

Amoxicillin vs. ceftriaxone: What's the difference?

  • Amoxicillin and ceftriaxone are antibiotics used to treat bacterial infections of the middle ear, tonsils, throat, respiratory tract, urinary tract, and pare.
  • Amoxicillin is also used to treat gonorrhea.
  • Ceftriaxone is besides used to care for pelvic inflammatory disease, bacterial septicemia, bone and joint infections, and meningitis.
  • Make names of amoxicillin include Moxatag and Amoxil.
  • A brand name for ceftriaxone is Rocephin.
  • Amoxicillin and ceftriaxone belong to different classes of antibiotics. Amoxicillin is a penicillin-type antibody and ceftriaxone is a cephalosporin antibiotic
  • Side furnishings of amoxicillin and ceftriaxone that are like include diarrhea, dizziness, nausea, vomiting, and rash.
  • Side effects of amoxicillin that are different from ceftriaxone include heartburn, slumber problems (insomnia), abdominal pain, itching, confusion, easy bruising, bleeding, and allergic reactions.
  • Side effects of ceftriaxone that are different from amoxicillin include upset stomach, blood clots, headache, pain or swelling in your tongue, a lump where the medicine was injected, sweating, vaginal itching or belch, vaginal yeast infection, anemia, changes in taste, or flushing.

What is amoxicillin? What is ceftriaxone?

Amoxicillin is a penicillin-blazon antibiotic, the same class that includes piperacillin (Pipracil), ampicillin (Unasyn), and ticarcillin (Ticar). Penicillin-type antibiotics do not straight kill bacteria, simply they finish bacteria from multiplying by preventing leaner from forming the walls that surround them. The walls protect bacteria from their environment and keep the contents of the bacterial cell together. Bacteria cannot survive without a cell wall. Amoxicillin is effective against many different bacteria including H. influenzae, Eastward. coli, Pneumococci, Due north. gonorrhoea, Streptococci, and some strains of Staphylococci. Amoxicillin is used to treat bacterial infections of the middle ear, tonsils, throat, larynx (laryngitis), lungs (pneumonia), bronchi (bronchitis), urinary tract, and pare. Amoxicillin as well is used to treat gonorrhea.

Ceftriaxone is a cephalosporin antibiotic used to care for a broad diversity of bacterial infections such equally lower respiratory tract infections, skin and peel construction infections, urinary tract infections, pelvic inflammatory affliction, bacterial septicemia, bone and joint infections, and meningitis. It works by stopping the growth of leaner.

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What are the side furnishings of amoxicillin and ceftriaxone?

Amoxicillin

Side effects due to amoxicillin include

  • diarrhea,
  • dizziness,
  • heartburn,
  • insomnia,
  • nausea,
  • itching,
  • vomiting,
  • confusion,
  • abdominal hurting,
  • like shooting fish in a barrel bruising,
  • bleeding,
  • rash, and
  • allergic reactions.

People who are allergic to the cephalosporin class of antibiotics, which are related to the penicillins, for instance, cefaclor (Ceclor), cephalexin (Keflex), and cefprozil (Cefzil), may or may not be allergic to penicillins.

Serious just rare reactions include:

  • seizures,
  • astringent allergic reactions (anaphylaxis), and
  • low platelet (thrombocytopenia) or red claret cell count.

Amoxicillin can alter the normal bacteria in the colon and encourage overgrowth of some bacteria such every bit Clostridium difficile which causes inflammation of the colon (pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting amoxicillin (diarrhea, fever, abdominal pain, and possibly shock) should contact their doctor immediately.

Ceftriaxone

You should non utilize this medicine if you have ever had a astringent allergic reaction to ceftriaxone or any other cephalosporin antibiotic. Go emergency medical help if you lot take signs of an allergic reaction (hives, difficult animate, swelling in your face or throat) or a severe skin reaction(fever, sore throat, called-for in your eyes, skin hurting, ruby-red or regal skin rash that spreads and causes blistering and peeling).

Call your md at once if you have:

  • a seizure (convulsions);
  • severe stomach hurting, diarrhea that is watery or encarmine;
  • sudden weakness or ill feeling, fever, chills, cold or influenza symptoms, mouth sores;
  • pale or yellowed skin, dark colored urine;
  • severe hurting in your upper stomach that comes and goes or spreads to your dorsum;
  • a claret jail cell disorder--skin rash or tight feeling, severe tingling or numbness, hurting, muscle weakness; or
  • kidney or bladder problems--hurting in your side or lower back spreading to your groin, claret in your urine, painful or hard urination, footling or no urine.

Common side effects may include:

  • mild diarrhea;
  • warmth, tight feeling, or a hard lump where the injection was given;
  • vaginal itching or discharge;
  • rash; or
  • abnormal liver function tests.

This is not a consummate list of side effects and others may occur. Call your doctor for medical advice most side furnishings. Y'all may written report side effects to FDA at one-800-FDA-1088.

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What is the dosage of amoxicillin vs. ceftriaxone?

Amoxicillin

  • For most infections in adults the dose of amoxicillin is 250 mg every eight hours, 500 mg every eight hours, 500 mg every 12 hours or 875 mg every 12 hours, depending on the type and severity of infection.
  • For the treatment of adults with gonorrhea, the dose is 3 yard given as one dose.
  • For virtually infections, children older than iii months but less than forty kg are treated with 25 or 45 mg/kg/mean solar day in divided doses every 12 hours or 20 or 40 mg/kg/twenty-four hour period with one-third of the daily dose given every 8 hours depending on the type and severity of the infection.
  • Amoxicillin tin be taken with or without nutrient.

Ceftriaxone

  • The usual adult daily dose is one to two grams given once a solar day (or in equally divided doses twice a day) depending on the type and severity of infection. The total daily dose should non exceed 4 grams.
  • Ceftriaxone is injected into a muscle, or into a vein through an IV.
  • A healthcare provider will give you this injection when ceftriaxone is used to prevent infection from surgery.
  • You may be shown how to use an IV at home to care for an infection. Do not requite yourself this medicine if you do non understand how to use the injection and properly dispose of needles, IV tubing, and other items used.
  • Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

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What drugs collaborate with amoxicillin and ceftriaxone?

Amoxicillin

Amoxicillin is rarely associated with important drug interactions.

Ceftriaxone

Rocephin must not be administered simultaneously with calcium-containing Iv solutions, including continuous calcium-containing infusions such every bit parenteral nutrition via a Y-site. All the same, in patients other than neonates, Rocephin and calcium-containing solutions may be administered sequentially of i another if the infusion lines are thoroughly flushed between infusions with a compatible fluid.

Other drugs may interact with ceftriaxone, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or terminate using.

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Are amoxicillin and ceftriaxone prophylactic to use while pregnant or breastfeeding?

Amoxicillin

  • Penicillins are generally considered rubber for use by pregnant women who are not allergic to penicillin.
  • Pocket-sized amounts of amoxicillin may be excreted in breast milk and may crusade diarrhea or allergic responses in nursing infants. Amoxicillin is generally considered safety to utilize while breastfeeding. Amoxicillin is used to care for infections in the newborn.

Ceftriaxone

  • Reproductive studies take been performed in mice and rats at doses up to 20 times the usual homo dose and have no evidence of embryotoxicity, fetotoxicity or teratogenicity. In primates, no embryotoxicity or teratogenicity was demonstrated at a dose approximately three times the man dose.
  • There are, however, no acceptable and well-controlled studies in pregnant women. Because animal reproductive studies are not e'er predictive of man response, this drug should be used during pregnancy just if clearly needed.
  • Low concentrations of ceftriaxone are excreted in human milk. Caution should be exercised when Rocephin is administered to a nursing adult female.

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Written report Problems to the Nutrient and Drug Administration

Y'all are encouraged to report negative side furnishings of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

References

FDA Prescribing Data.

Some content virtually ceftriaxone is used courtesy of the U.S. Food and Drug Administration

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Source: https://www.medicinenet.com/amoxicillin_amoxil_vs_ceftriaxone_rocephin/article.htm

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